At Destination Aesthetics™, we’re proud to bring one of the most innovative advances in healing skin treatments to our patients across El Dorado Hills, Elk Grove, Folsom, Roseville, and Sacramento, CA: Ariessence™ pure PDGF+. This medical-grade topical solution harnesses platelet-derived growth factor (PDGF), one of the body’s most powerful natural proteins for tissue repair and renewal, combined with hydrating hyaluronic acid for soothing, consistent results.
Ariessence™ pure PDGF+ is a medical-grade regenerative serum. It elevates skin rejuvenation results both immediately and long term. It combines recombinant platelet-derived growth factor (PDGF), the most studied tissue growth factor in regenerative medicine, with sterile hyaluronic acid (HA) for hydration and barrier support.
Doctors have treated over 5 million patients with PDGF in other FDA-approved medical treatments, proving its safety through extensive research. We apply Ariessence™ to your skin after procedures such as microneedling, MOXI®, or laser skin treatment to reduce redness, shorten downtime, and stimulate collagen remodeling for smoother, firmer, and more radiant skin.
The cost of Ariessence™ depends on the number of vials required, treatment areas, and whether it’s paired with other rejuvenating services such as microneedling or laser. While many patients require 2 to 3 sessions spaced several weeks apart for optimal results, your provider will customize a plan based on your goals, skin condition, and recovery needs. During your consultation, we’ll provide transparent pricing and recommendations so you know exactly what to expect.
At Destination Aesthetics™, we’re always looking for ways to bring our patients the most advanced, effective, and safe innovations in skin rejuvenation. That’s why we’re proud to offer Ariessence™ pure PDGF+, a next-generation topical solution designed to enhance recovery, refine texture, and restore radiance after aesthetic procedures.
What sets Ariessence™ apart is its balance of immediate soothing hydration and long-term regenerative benefits. Patients often notice reduced redness and downtime within days, along with steadily improving tone, smoothness, and elasticity as the treatment activates collagen production. Ariessence™ gives our patients a new standard in skin health and post-treatment confidence.
A #DAG is a Destination Aesthetics™ girl or guy who believes in equality, freedom, love, acceptance, and peace.
As nurse practitioners, registered nurses, and licensed estheticians, we combine our years of experience and artistry in our craft with a passion for bringing out the very best in you. We are family-centric teammates on a mission to help you live your best and most beautiful life.
Stimulates collagen and elastin for firmer, more youthful skin
Hydrates and strengthens the skin barrier for lasting glow
Reduces post-procedure redness and downtime
Enhances results of treatments like microneedling, MOXI®, and lasers
Smooths fine lines, wrinkles, and uneven texture
Provides a consistent alternative to PRP, PRF, and exosomes
While PRP (platelet-rich plasma) and exosome therapies are also used to support skin rejuvenation, Ariessence™ pure PDGF+ offers several distinct advantages. Traditional PRP requires a blood draw and centrifuge process, while exosomes often raise questions around cleanliness and reliability. Ariessence™, on the other hand, is a medical-grade, sterile, and predictable mixture that delivers far higher concentrations of growth factors without the variability. This makes it a safe, effective, and time-efficient alternative for patients seeking visible results with confidence.
Best for
Post-procedure recovery, collagen stimulation, improved skin texture, reduced downtime, consistent rejuvenation
General skin rejuvenation, variable results depending on source quality
Results begin
Immediate soothing; visible collagen improvement within weeks, compounding over several months
Initial plumping or brightening after treatment; collagen response varies
Results last
6–12 months or longer with collagen stimulation; many patients maintain improvements up to 2 years
Typically 3–6 months depending on patient’s blood quality (PRP) or exosome preparation
Treatment Areas
Face, neck, chest, scalp for hair restoration, hands
Face, neck, scalp, variable based on provider
Treatment Feel
Comfortable topical or post-procedure application; no blood draw or invasive prep
Requires blood draw (PRP) or biologic sourcing (exosomes); variable sterility and comfort
Best for
Deeper wrinkles, significant sun damage, texture irregularities, tightening skin
Results begin
More dramatic, long-lasting improvements after a single treatment series (usually 1–3 laser sessions spaced a few months apart)
Results last
1–3 years, depending on skin condition and aftercare (touch-ups may be needed every few years)
Treatment Areas
Primarily face and neck; sometimes chest, but not typically used on larger body areas
Treatment Feel
Heat sensation, often numbing cream applied for comfort
Healthy, confident skin isn’t just for women. At Destination Aesthetics™, we’ve seen more men turning to advanced treatments like Ariessence™ pure PDGF+ to boost their results and speed up recovery. Whether used after microneedling, laser, or other rejuvenating services, Ariessence™ helps minimize redness, improve texture, and restore a refreshed appearance without looking overdone.
Our providers tailor every application with men’s unique needs in mind, focusing on subtle, natural improvements that enhance masculine features.
Ariessence™ pure PDGF+ is designed to work well with a wide range of beauty treatments, making it a versatile addition to your treatment plan. Because it supports natural collagen stimulation and skin repair, it pairs great with procedures that target skin renewal. Adding Ariessence™ enhances recovery, reduces downtime, and amplifies your visible results.
EXCELLENT Based on 256 reviews Posted on John CTrustindex verifies that the original source of the review is Google. Always easy fun experience, quick and painless for the most part 🤭Posted on John CTrustindex verifies that the original source of the review is Google. First time having laser treatment for broken capillaries but very easy appointment and jessica was very friendly, nice and professional. I’m going back before my Botox soon !😊
Owner's reply
Thank you for your positive feedback about our practice! Jessica has been in the aesthetic industry for over 8 years and continues to give the best experience possible! All our best, Destination AestheticsPosted on Arielle MTrustindex verifies that the original source of the review is Google. I’ve recently switched to Jessica, because my prior work was done by someone no longer working in Elk Grove. I’ve always been happy at destination aesthetics. The one time I didn’t come here I ended up with lop sided eyebrows and had to come back for destination to fix it. They always keep your follow up appointment. They always make you comfortable. Jessica had extensive knowledge of the laser facial and best sunblock options. The entire time I felt like I was hanging out with a friend (a smart friend) 10/10 would recommendPosted on Bev BTrustindex verifies that the original source of the review is Google. Great results with Cool Sculpting. Very pleased. Ryan is a phenomenal provider. Highly recommend Cool Sculpting, Ryan and DA. 🤗
Owner's reply
Hi Bev, thank you very much for your wonderful review! We agree that Ryan is a phenomenal provider! Your feedback is important to us and we cannot wait to share it with our team! All our best, Team DAPosted on Alee BTrustindex verifies that the original source of the review is Google. I got my facial with Bella and she is the best.
Owner's reply
Thank you so much! All our best, Team DAPosted on Michele WTrustindex verifies that the original source of the review is Google. Good customer service and professional work. It is much easier than driving to Sacramento.
Owner's reply
Thank you for the 5-Star review, Michele!Posted on Tatiana DTrustindex verifies that the original source of the review is Google. Jessica is a sweetheart! First time doing botox and she was so patient and explained everything plus more! She genuinely loves what she does. Thank you Destination Aesthetics - Elk Grove!
Owner's reply
Hi Tatiana, thank you for the positive feedback about our Registered Nurse, Jessica! We appreciate you taking the time leave us a 5-Star review! All our best, Team DAPosted on Nicole HTrustindex verifies that the original source of the review is Google. Jessica is the absolute best! She is great at her job as well as pure joy to be around!
Owner's reply
Thank you for your kind words about our Registered Nurse, Jessica! We appreciate you taking the time to leave us feedback!Verified by TrustindexTrustindex verified badge is the Universal Symbol of Trust. Only the greatest companies can get the verified badge who has a review score above 4.5, based on customer reviews over the past 12 months. Read more
We designed your Ariessence™ appointment to be simple, comfortable, and highly effective. Most treatments take less than an hour and can be easily added to your existing aesthetic routine. Because Ariessence™ is a medical-grade solution that is applied on the skin, there is no blood draw or lengthy prep-time involved.
Step 1
During your private consultation, your provider will review your goals and skin concerns. Together, you’ll decide the best treatment approach and whether Ariessence™ will be used alone or in combination with other services.
Step 2
After cleansing the skin, your provider applies Ariessence™ to your skin during or after treatment (such as after microneedling or laser). Its blend of PDGF and hyaluronic acid penetrates deeply to encourage collagen production, hydration, and healing.
Step 3
There is little to no downtime with Ariessence™. Most clients notice immediate soothing and gradual improvements over the following weeks as collagen renewal takes place. You’ll leave your appointment with your skin feeling refreshed, calm, and supported in its natural rejuvenation process.
Safety and trust are at the core of every treatment we offer, and Ariessence™ pure PDGF+ is no exception. FDA-regulated facilities manufacture this medical-grade skin solution under strict quality standards. Each treatment delivers a clean, consistent amount of growth factors and hyaluronic acid, free from human or animal products. Unlike therapies that rely on a patient’s own blood, Ariessence™ eliminates unknown differences and delivers a predictable experience every time.
Possible side effects with Ariessence™, while uncommon and typically very mild, may include temporary changes at the application site that are short-lived and self-resolving.
Your provider will give you aftercare guidance to maximize your comfort and results, but the vast majority of patients find Ariessence™ to be one of the smoothest, easiest additions to their aesthetic routine.
Most patients begin with a series of two to three Ariessence treatments, spaced about six to eight weeks apart. This allows the pure PDGF+ to bost steady collagen production and support long-term improvements in skin quality. Your injector customizes your plan based on your skin’s condition, your goals, and whether you’re combining Ariessence with procedures like microneedling or laser resurfacing.
Yes. Ariessence is often paired with resurfacing treatments or RF microneedling to soften the appearance of acne scars and smooth out rough texture. Because it stimulates collagen and enhances skin healing, patients typically notice more refined, even-toned skin over the weeks following treatment. Many find it helps minimize the look of old scars and pores while boosting overall radiance.
Results vary depending on the treatment area and individual factors, but many patients enjoy improvements for 6 months to a year or longer. As collagen continues to rebuild, benefits such as firmer skin, smoother lines, and improved tone become more noticeable. Regular maintenance sessions and a good skincare routine help extend your glow and keep results consistent over time.
Absolutely. Ariessence is made without human or animal components and is produced under medical-grade standards, making it well suited for sensitive or reactive skin. Because it contains only a handful of highly purified ingredients, it avoids the unpredictability of treatments like PRP or exosomes. Most clients tolerate it extremely well, even when applied after procedures that leave skin more vulnerable.
Unlike PRP, Ariessence does not require a blood draw, and it eliminates changes in growth factor concentration. Compared to exosome products, which may carry cleanliness or sourcing concerns, Ariessence offers a consistent, clean mixture with up to 300,000 times the number of growth factors. This makes it a more predictable, safe, and effective option for patients seeking advanced skin treatments.
Downtime is minimal. Most clients experience only mild redness or swelling that fades within a day or two. Because of its soothing hyaluronic acid component, Ariessence often reduces post-procedure inflammation and helps patients feel comfortable getting back to their daily routine right away.
Yes, Ariessence can be applied after laser treatments or injected into the scalp to support stronger, fuller hair growth. By reducing inflammation and stimulating local repair, it helps create a healthier environment for hair follicles. Patients often notice improvement in density and thickness within several months when used as part of a comprehensive hair restoration plan.Retry
If you would like more information about Destination Aesthetics and the services we provide, give us a call! We would be happy to sit down and talk to you about your cosmetic options and answer any questions that you may have.
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